Ich bin nun mehr als drei Jahren Kundin bei Dr. Grittern und unfassbar glücklich damit! Mich hat ihre hohe Fachexpertise, ihre individuelle Beratung und selbstverständlich die tollen Ergebnisse überzeugt.
Sie hat einen tollen Sinn für Ästhetik! Die Behandlungen führt sie präzise, sicher und ohne Komplikationen durch.
Zudem hat sie ein tolles Team!
In dieser schönen Praxis kann man sich nur wohl fühlen.
(Dafür nehme ich gerne zwei Stunden Autofahrt in Kauf.)
Would you like to give your skin new vitality and radiance? Innovative skin rejuvenation with polynucleotides is revolutionizing aesthetic dermatology and offers a state-of-the-art alternative to conventional anti-aging treatments. At our first-class Skinthetics practice in Düsseldorf, we rely on this pioneering technology to help you achieve a radiant, youthful skin appearance.
Polynucleotides treatments are among the most innovative developments in regenerative medicine. These biological agents stimulate your skin's natural healing and regeneration processes at the cellular level. Our specialist Dr. Lucija Grittern uses state-of-the-art equipment and the latest global standards to offer you customized treatment concepts in a luxurious setting.
Facts about skin rejuvenation with polynucleotides in Düsseldorf
- Treatment duration
- 30-45 minutes
- Anesthesia
- Local anesthesia possible
- Aftercare
- Minimal
- Social acceptability
- Immediate
- Sports
- After 24-48 hours
- Cost
- Starting at 400€
What our patients say

Important information about skin rejuvenation with polynucleotides in Düsseldorf
What are polynucleotides?
Polynucleotides are high-molecular biological compounds obtained from DNA fragments. These natural active ingredients play a crucial role in cell regeneration and tissue renewal. In aesthetic medicine, they are used as innovative injection solutions to promote skin rejuvenation at the molecular level.
The polynucleotides used are produced using a special process and are highly purified. Due to their high biocompatibility, they are optimally absorbed and utilized by the human body. These active ingredients have the unique property of repairing damaged cells and stimulating Collagen production.
Dr. Lucija Grittern uses only high-quality polynucleotide preparations that meet the highest safety standards in our Düsseldorf practice. The treatment is carried out by targeted microinjections into the relevant skin layers.
What is skin rejuvenation with polynucleotides and how do polynucleotides work?
Skin rejuvenation with polynucleotides is based on the principle of biological regeneration. After injection, the polynucleotides unfold their triple effect: they stimulate Collagen and elastin production, promote cell regeneration, and improve blood circulation in the treated areas.
Polynucleotides act as biological repair molecules that can recognize and repair damaged DNA structures in skin cells. This process leads to a significant improvement in skin quality from the inside out. The active ingredients activate fibroblasts, which are responsible for the production of structural proteins.
A particular advantage of Polynucleotides is their antioxidant effect. They neutralize free radicals and protect the skin from further damage caused by environmental influences. At the same time, the skin's natural moisture is improved, as Polynucleotides increase the water storage capacity of the cells.
Our expert Dr. Lucija Grittern explains: "Polynucleotides before and after results often show a significant improvement in skin structure after just a few weeks." The treatment is particularly suitable for patients who are looking for a natural alternative to synthetic fillers.
Our Expert
Dr. med. Lucija Grittern
Dr. Lucija Grittern has over 18 years of top-level training, from the University of Edinburgh to clinical placements in London and Charité, to international training highlights in Los Angeles and Brazil. Her expertise is backed up by specialist publications, media activities, and lectures.
Since 2018, she has been fulfilling her dream with Skinthetics, offering natural, comprehensive skin health at the highest level in Düsseldorf – with precision, empathy, and state-of-the-art aesthetic medicine.
How does a polynucleotide treatment at Skinthetics work?
Preparation for treatment
Before each Polynucleotides treatment, our team conducts a detailed medical history and skin analysis. Dr. Lucija Grittern assesses your individual skin type and creates a customized treatment plan. Your personal wishes and expectations are taken into account.
During an initial consultation, we will explain the procedure, possible side effects, and the expected results. Before the treatment, the skin is thoroughly cleansed and disinfected. If necessary, a local anesthesia can be applied.
Performing the treatment
The polynucleotides treatment is performed using precise microinjections with very fine needles. Our specialist injects the polynucleotides directly into the relevant skin layers. The treatment is usually painless, as we use the latest injection techniques.
Different injection depths are selected depending on the treatment area. The entire session lasts about 30 minutes. During the treatment, we continuously monitor your well-being and adjust the technique if necessary.
Aftercare
After the polynucleotides treatment, slight redness or swelling may occur, which usually subsides within a few hours. Our team will provide you with detailed aftercare instructions. Special aftercare is not usually necessary.
You will be able to socialize immediately after the treatment and resume your normal activities. Only intense sun exposure and sports should be avoided for the first 24-48 hours.
Our new practice

Our high-end clinic


Our new clinic is located just a few minutes’ walk from our previous premises. We look forward to welcoming you in a stylish, modern setting – designed for calm, comfort, and a relaxed treatment experience.
See for yourself on your next visit.
We are delighted to welcome you to our new clinic.
Advantages of polynucleotide treatment with expert Dr. Lucija Grittern
- State-of-the-art equipment with the latest injection technology
- Years of expertise in aesthetic Dermatology
- Individual treatment concepts for optimal results
- Luxurious practice atmosphere in a central location in Düsseldorf
- Comprehensive consultation and professional aftercare
- Use of high-quality polynucleotide preparations
- Holistic treatment concept for lasting results

FAQ – Frequently asked questions about polynucleotide treatment
Which treatment areas are suitable for treatment with Polynucleotides?
Polynucleotides can be used on various areas of the body. We particularly often use the treatment for fine wrinkles under the eyes.
What results can be expected from polynucleotide treatment?
The results include a significant improvement in skin structure, increased elasticity, and a natural skin glow. Fine lines are reduced and the overall skin quality improves noticeably.
When can one expect results?
Initial improvements are often visible after just 2-3 weeks. The final result develops over a period of 6-8 weeks, as the regeneration processes take time.
How many treatments are necessary?
For optimal results, we generally recommend 2-3 treatments at intervals of 3-4 weeks. Dr. Lucija Grittern will create an individual treatment plan based on your skin type.
How painful is a polynucleotide treatment?
The treatment is usually painless. Most patients report a slight stinging sensation during the injections. We use local anesthesia if necessary.
What should I keep in mind after a polynucleotide treatment?
Avoid intense sun exposure and exercise for the first 24 hours. Use the skincare products we recommend and drink plenty of water.
Are there any risks or side effects associated with polynucleotide treatment?
Polynucleotides are well tolerated. Occasionally, slight redness, swelling, or small bruises may occur, but these subside quickly. Serious side effects are very rare.
How much does polynucleotide treatment cost at Skinthetics?
The cost of polynucleotides treatment starts at €400. The exact price depends on the scope of treatment and the number of sessions.

